Zarin is a graduate student in the Biochemistry, Biophysics and Chemical Biology (BBCB) group. She graduated from the University of North Carolina at Chapel Hill in 2020 with a B.S. in biochemistry and neuroscience. As a member of Todd Cohen’s lab, she studied the regulation of the kinase MARK2 and acetyltransferase CBP, which are implicated in the protein tau’s aggregation in AD. She was born in Dhaka, Bangladesh and raised in Muncie, Indiana. In her free time, she likes to read, play tennis, play video/table-top games, spend time with friends/family, and explore Philly. In 2020, Zarin was awarded an National Science Foundation Graduate Research Fellowship.

Publications

Tabassum, Z., J-H. Tseng, C. Isemann, X. Tian, Y. Chen, L.E. Herring, and T.J. Cohen. (2022). Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase. J. Biol. Chem.298(6):101977. pdf file link

Tseng, J-H., A. Ajit, Z. Tabassum, N. Patel, X. Tian, Y. Chen, A.W. Prevatte, K. Ling, F. Rigo, R.B. Meeker, L.E. Herring, and T.J. Cohen. (2021). Tau seeds are subject to aberrant modifications resulting in distinct signatures. Cell Rep. 35(4):109037. pdf file link

Trzeciakiewicz, H., D. Ajit, J-H. Tseng, Y. Chen, A. Ajit, Z. Tabassum, R. Lobrovich, C. Peterson, N.V. Riddick, M.S. Itano, A. Tripathy, S.S. Moy, V.M.Y. Lee, J.Q. Trojanowski, D.J. Irwin, and T.J. Cohen. (2020). An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline. Nat. Comm. 11:5522. pdf file link